July 2, 2001: Signs with the Phillies after they drafted him in the fifth round.
2003: Named the Florida State League MVP after batting .304 with 23 homers and 82 RBIs with high-A Clearwater.
2004: Chosen the Eastern League MVP after hitting 46 homers with double-A Reading to lead all of minor-league baseball.
Sept. 1, 2004: Makes major-league debut and 10 days later he hits his first major-league homer off Mets righthander Bartolome Fortunato.
2005: Howard spends most of the season's first half in triple A as he is blocked at first base by Jim Thome. Thome's injuries open up time for Howard, who despite just 28 at-bats before July 1 leads all National League rookies in homers (22) and slugging percentage (.567) and is second in RBIs with 63. He is the first Phillies player to win the Rookie of the Year Award since Scott Rolen in 1997.
Nov. 25, 2005: The Phillies trade Thome to the White Sox, which allows Howard to be the full-time first baseman.
March 2006: Sets a Phillies spring training record with 11 homers, serving as a precursor of things to come.
May 14, 2006: After spending the previous night in a Cincinnati hospital with food poisoning, comes off the bench to hit a tying homer in the eighth and wins the game with another homer in the 12th.
June 20, 2006: Hits two homers - including a 461-foot shot to the third deck in right field - and drives in seven runs against the Yankees.
July 10, 2006: Wins the Home Run Derby at PNC Park in Pittsburgh, defeating the Mets' David Wright in the final round.
Sept. 3, 2006: Homers three times off the Braves' Tim Hudson to become the 17th Phillies player to homer three times in a game.
Sept. 22, 2006: Hits his 58th homer of the season to establish the franchise's single-season record.
Nov. 20, 2006: Wins the National League's MVP Award to become just the second player in history (Cal Ripken Jr. was the first) to win the Rookie of the Year and MVP awards in consecutive seasons.
June 27, 2007: Reaches 100 home runs in 325 games, faster than any player in history, breaking the previous record (385 games) set by Ralph Kiner. He will become the fastest to 150, 200 and 250 as well.
July 25, 2007: Hits a walk-off homer just as the clock strikes midnight to lift the Phillies over the Nationals in a wild 14-inning game.
Aug. 28, 2007: Hits another walk-off homer, this time against the Mets to win the second game of what would be a pivotal four-game sweep.
Sept. 30, 2007: Homers in his final four games of the season as the Phillies erase a seven-game deficit with 17 games to play to shock the Mets and win the National League East.
Feb. 1, 2008: Wins his salary arbitration case and is awarded a $10 million contract (Phillies had offered $7 million). It's the highest figure ever given to a player who has won an arbitration case and the first time the Phillies lose a case.
Aug. 11, 2008: Drives in his 100th run to become the second player in Phillies history to record three-straight 100 RBI, 30-homer seasons.
September 2008: Named the National League's player of the month as he helps the Phillies rally again past the Mets for the division title. His 32 September RBIs are the most in September month by any Phillies player, and 25 of his final 40 hits go for extra bases.
Oct. 26, 2008: Howard homers twice as the Phillies rout Tampa Bay in Game 4 of the World Series. Three nights later, Howard will sprint in from first base to tackle Carlos Ruiz and Brad Lidge at the mound to celebrate the team's first World Series title in 28 years.
Feb. 8, 2009: Signs a three-year, $54 million contract that buys out Howard's final three years of salary arbitration.
May 30, 2009: Hits a 475-foot grand slam into the first row of the third deck in right field at Citizens Bank Park.
October 2009: Named the MVP of the National League Championship Series after hitting .333 with two homers and eight RBIs against the Dodgers, helping the Phillies reach the World Series in consecutive years for the first time in franchise history.
April 26, 2010: Signs a five-year, $125 million contract, with a club option for 2017. He remains under this contract as this season comes to an end.
Aug. 1, 2010: Misses 16 games with a left ankle sprain, which he injured running to second base.
Oct. 23, 2010: Makes the final out - a strikeout looking on a 3-2 count - as the Phillies are eliminated by San Francisco at Citizens Bank Park in Game 6 of the National League Championship Series.
Oct. 1, 2011: Hits a three-run homer in the sixth to propel the Phillies to a series-opening win over St. Louis in the National League Division Series.
Oct. 7, 2011: Makes the final out, a grounder to second base, as St. Louis eliminates the Phillies in Game 5 at Citizens Bank Park. Howard suffers a torn left Achilles on the swing as he falls to the ground on his way to first bases. He has surgery five days later and his career will never be the same.
July 6, 2012: Returns from the disabled list after missing the season's first three months due to his Achilles injury the previous October.
Sept. 22, 2012: Hits his 300th career homer but will break the big toe on his right foot five days later when he drops a weight on it in the on-deck circle.
July 6, 2013: He is placed on the disabled list with left knee inflammation and will miss the remainer of the season.
May 31, 2014: Records his 1,000th career RBI, and will finish the season fourth in the National League with 95 RBIs. He bats just .223 in 2014 and leads the majors with 190 strikeouts.
Aug. 24, 2015: Reaches 20 home runs in a season for the ninth time, second in Phillies history only to Mike Schmidt's 14.
April 29, 2016: Hits a walk-off homer in the 11th to beat Cleveland, the sixth walk-off homer of his career.
Sept. 27, 2016: Hits his second grand slam of the season and a franchise-record 15th of his career. Schmidt is second with seven.