The Eagles needed four drives to record a first down. The starting defense forced two turnovers.
The Buffalo receiver from Burlington Twp., N.J. suffered a foot injury, the Bills said.
Carson Wentz went back out for a fourth series and got his first completion with Alshon Jeffery.
The Eagles defensive end showed visible support of Jenkins, who has been protesting racial injustice in America.
The Eagles' second preseason game kicks off soon after 7 p.m.
Matt Tobin started at right tackle. The line struggled early in the game.
He wasn't awful in 2016. But he also wasn't good enough to support the assumption that he will be a game-changing upgrade over Sproles, Smallwood and Mathews.
Wentz expects a "loud" crowd in the first preseason game at Lincoln Financial Field.
Rasul Douglas is three years removed from playing at a community college and worrying about getting enough to eat. His drive has sustained him.
Wendell Smallwood, a second-year runner, has the chance to become the latest Eagles backfield hero.
The Eagles have six former Bills on their roster. The Bills have four former Eagles.
The Phillies followed in a close second while the Eagles finished dead last.
Ryan Mathews' release has been pending since January; now the elaborate, salary-cap-related dance has finally ended.
Ronald Darby and Alshon Jeffery should take the field for the first time as Eagles Thursday, as Nelson Agholor tries to fill Jordan Matthews' big shoes.