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John Robertson rallied his team to a come-from-behind, 49-31 victory over James Madison.
Penn's first venture into Florida did not prove to be a pleasant trip.
Backup Sean Maguire hung it with an up-and-down effort as Florida State escaped with a 23-17 overtime victory.
D'Angelo Roberts scored on a 3-yard touchdown run to help Indiana upset No. 18 Missouri 31-27.
Marcus Mariota threw for 329 yards and five touchdowns as No. 2 Oregon held off Washington State 38-31.
Samaje Perine ran for 242 yards and four touchdowns to lead No. 4 Oklahoma to a 45-33 win.
The Bulldogs survived a furious fourth-quarter rally by No. 8 LSU to snap a 14-game skid in the series, 34-29.
Blake Sims threw for 445 yards, and the No. 3 Crimson Tide overcame a sloppy performance to beat Florida 42-21.
Kenny Hill accounted for 322 yards of offense in just the first half, and sixth-ranked Texas A&M rolled.
Sony Michel ran for 155 yards and three touchdowns during No. 13 Georgia's 66-0 win over Troy.
The Temple defense and special teams have scored touchdowns in four straight outings dating back to last season.
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