The Wildcats play at Georgetown and new head coach Patrick Ewing. Temple, La Salle and St. Joe's are at home.
Temple freshman Nate Pierre-Louis was named this week's American Athletic Conference Rookie of the Week after scoring a career-high 23 points in Saturday's 75-72 overtime loss to visiting Memphis.
Patrick Ewing leads Georgetown against Villanova as head coach of the Hoyas.
Duke was the ACC's preseason favorite and North Carolina the defending national champion.
The Big East might be the highest-scoring conference in the country, and it's not because no one can play defense.
The NBA all-star is contributing the largest single donation by a former Wildcats basketball player.
Top-ranked Villanova relied on its defense to hold off St. John's on Saturday at Madison Square Garden.
The top-ranked Wildcats will play struggling St. John's on Saturday at Madison Square Garden.
Georgetown legend Patrick Ewing and St. John's star Chris Mullin are trying to bring back the glory to their alma maters.
Villanova's point guard is playing at a historically high level, leading the Wildcats to the top national ranking.
No.1 Villanova took on 10th-ranked Xavier and easily handled the Musketeers ??-?? at the Wells Fargo Center.
He has the eligibility to play another season at 'Nova but is also a potential lottery pick in the 2018 NBA draft.
Wednesday night's action is highlighted by a Wells Fargo Center showdown between No. 1 Villanova and No. 10 Xavier.