This is the third straight year that the Owls are facing a top ranked Villanova team.
With Duke and Kansas suffering upset losses, the Wildcats took the top spot in the Associated Press and USA Today coaches rankings.
"Someone fell on his hand in practice," Wright said of Gillespie after the Wildcats' win over La Salle.
The Wildcats (10-0) earned 41 of 65 first-place votes to hop over Michigan State, which some observers had expected to take the top spot.
The Wildcats (10-0, 3-0 Big Five) won their 21st consecutive City Series game. Jalen Brunson helped secure the victory.
After sitting out as a redshirt last season, Phil Booth has returned to become a primary component in the Wildcats lineup.
The Wildcats remained undefeated with a win over 12th-ranked Gonzaga on Tuesday night at Madison Square Garden.
Mikal Bridges scored a career-high 28 points and Phil Booth added 20 for the Wildcats.
Alabama beat out Ohio State for the fourth and final spot in the college football playoffs. Penn State will play Washington in the Fiesta Bowl on Dec. 30. Temple is going to the Boca Raton Bowl to play Florida Atlantic on Dec. 19.
Mikal Bridges had 18 points and nine rebounds for Villanova as the Wildcats win their 20th straight Big Five game, and 18th in a row by double digits, over Saint Joseph's at Hawk Hill.
The first-year Villanova big man got going offensively and had the old building shaking in the victory over Penn.
Jalen Brunson led the way with 17 points as Villanova beat Penn, 90-62, at Jake Nevin Field House to keep their Big Five streak alive.
The Wildcats will play their first City Series game Wednesday at Jake Nevin Field House against Penn. They have won 18 straight Big Five games.