She had the lead heading into the homestretch but ultimately faded and finished in 2 minutes, 5.73 seconds in her first NCAA outdoor final.
Former Villanova coach Andy Talley, Troy Vincent of Pennsbury, and Jahri Evans of Frankford are among other standouts on this year's ballot.
The Quakers have three incoming freshman, plus redshirt freshman Jelani Williams returning after missing last season while recovering from ACL surgery.
These are local athletes who also excelled as students.
The Palestra hosted the Ivy League tournament during its first two years in existence.
After the Wildcats' women continued their dominance at the carnival, their teammates on the men's side won behind a marvelous anchor leg from Casey Comber.
The carnival celebrates its 124th season of competition and is once again chock full of events on the track at Franklin Field with about 20,000 athletes participating.
The University of the Bahamas sophomore, and senior Tyanna Petty of Rio Grande (Ohio) in the heptathlon, lead going into Wednesday's final day of the multi-event competitions.
Donohue, who starred at Haddonfield High School and North Carolina before enjoying a fine pro career, returned for the carnival's kickoff event at a West Philadelphia school.
The Ivy League on Wednesday announced the most wide-ranging media rights deal in its history: a 10-year pact with ESPN that gives the network full rights to over 1,100 games from the conference's 30-plus varsity sports.
Whether or not anyone saw Loyola-Chicago making it to this year's Final Four, someone at the school had the sense back in 2011 to hire Porter Moser. That someone was Grace Calhoun.
Donahue has a good feel for both teams after his Quakers played both No. 1 seeds at different junctures of the season.
The Penn senior adds some measurables to an impressive NFL prospect resume.