Tramaine Isabell, a transfer from Missouri, led Drexel with 22 points.
Dragons leader Kurk Lee shot just 3-for-14 from the field, while Falcons guard Justin Turner poured in 33 points.
Kurk Lee, the super quick point guard from Baltimore, had some help last season, but not nearly enough.
The Dragons' guard rotation is five deep and they may use as many as four guards on the floor at once.
Kurk Lee is the leading returning scorer for Drexel after averaging 14.9 ppg. Sammy Mojica and Miles Overton are the top seniors.
Two of the first three games are against NIT qualifiers from last year, Akron and Houston. Drexel will visit La Salle and Temple.
After finishing 10th last season, the Dragons were picked ninth in the preseason poll. College of Charleston is the favorite, along with Towson, Hofstra and Elon.
"I have a whole family that enjoys every game that I play,'' Lee said. "This is bigger than me. It's family."
The two are competing for the Broad Street Brawlers in The Basketball Tournament.
The St. Joes mens varsity eight qualified for the grand final for the first time since 2005.
These multi-sport stars are looking ahead to the weekend's Dad Vail Regatta
Here is all you need to know about the three-day event that runs Thursday through Saturday at Franklin Field.
Villanova was the big winners of the Big Five awards announced Tuesday, with Josh Hart being named player of the year and Jay Wright winning coach of the year honors.