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Todd Gurley scored four total touchdowns, and No. 12 Georgia gained a 45-21 victory over No. 16 Clemson.
Blake Sims was good enough in his first start at quarterback, and the Crimson Tide held off West Virginia 33-23.
Marcus Mariota scored four total touchdowns, leading the third-ranked Oregon Ducks to a 62-13 victory.
Trevor Knight passed for 252 yards and a touchdown to help No. 4 Oklahoma defeat Louisiana Tech 48-16.
Redshirt freshman J.T. Barrett threw for 226 yards and two touchdowns in his college debut.
Jeremy Johnson and Nick Marshall returned led No. 6 Auburn to a 45-21 opening victory over Arkansas.
UCLA scored three defensive touchdowns in a 28-20 win over Virginia.
No. 11 Stanford tuned up for a date with No. 15 Southern California next week by routing UC Davis 45-0.
Cody Kessler threw for 394 yards and No. 15 USC ended a trying week with a 52-13 win over Fresno State.
Everett Golson led No. 17 Notre Dame to a 48-17 victory over Rice on Saturday.
Video: The Nittany Lions won in dramatic fashion to give James Franklin his first win at the school.
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