The two teams each average more than 80 points, but defense, rebounding and the Wildcats' ability to handle the press will be the keys.
Jay Wright has been Villanova's coach for 17 seasons. If he wants another challenge, this could be the time.
The East bracket wasn't marred with the first-weekend surprises that shook the other regions. So the top-seeded Wildcats get a tough regional-semifinal draw in No. 5 West Virginia.
"I always thought Villanova was consistent throughout the year in that you knew they were going to be there when the smoke cleared."
The tournament isn't perfect and the bracket was flawed, but not if your team made it this far.
The Wildcats' redshirt sophomore gained confidence playing Oklahoma's Buddy Hield on the scout team before the 2016 Final Four. He has starred this season as sixth man, and currently in the NCAA tournament.
Under Jay Wright, Villanova has become perhaps the best college basketball program in the country. Where does that put him on the city's all-time list of great coaches?
The two coaches faced off only six times in Big East play before West Virginia left the conference, but Villanova's coach called their relationship "very good."
The No. 1 seed Wildcats played West Virginia 23 times in Big East play from 1995-2012, and will face the fifth-seeded Mountaineers on Friday night in Boston.
The tight end has spoken with representatives from all 32 NFL teams.
Bodensteiner was senior associate athletic director at Notre Dame. She will replace Don DiJulia at St. Joe's
Next up for the Nittany Lions is Mississippi State
Tucker found out an extraordinary domestic violence situation involving an ex-boyfriend was grounds to grant her an extra semester.