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Diagnosing heart disease with a breathalyzer

What does your breath say about your health?

(Inside Science TV) – If police can detect alcohol on your breath … could doctors detect heart disease the same way?

"When people think of breath testing they think of the breathalyzer. If you can do that on the side of the road, you can potentially do it anywhere," said Raed Dweik, a pulmonologist at the Cleveland Clinic Respiratory Institute. Including the doctor's office!

"Breath has so many compounds that come out that you measure that can tell a lot about a person's health or disease," he said.

In fact, everyone has their own personal breath print. Now pulmonary specialists at the Cleveland Clinic are working with NASA engineers to read what your breath print says about your health.

"Everything in the blood that is potentially volatile comes up in the breath," said Dweik.

Thousands of molecules in the body are exhaled from the lungs. Volatile organic compounds evaporating into our breath reflect what's happening inside our bodies.

So far, researchers have been able to detect asthma, diabetes, liver disease and kidney disease from breath tests. But, there was one thing researchers didn't expect to find?

"We were completely blown away when we found out every single patient that comes in with acute decompensated heart failure has a unique breath print," said Dweik.

The typical breathalyzer could even detect different types of heart disease.

Kevin Decrane started feeling the symptoms of pulmonary arterial hypertension when he was just 35 years old. The right side of his heart was enlarged. It's a progressive and terminal disease.

"I'd be running up stairs and when I would get to the top of the stairs I'd get short of breath which really never happened before," said Decrane.

Decrane took the newly-developed breath test. The specimen from the test is filtered into a device called a mass spectrometer that helps identify the amount and type of chemicals present in breath.

From there, researchers will look for combinations of different molecules that can provide a sense of what's going on in the body.

For Decrane, it was proof of his diagnosis.

"It was surprising that they can analyze your breath and find out so much about what's going on with your body," said Decrane.

A quick breath test that could revolutionize how diseases are detected in the future.

"Breath testing is non-invasive, non-intrusive, it can be done repeatedly and almost anywhere. I call this the new frontier of medical testing" said Dweik.

Reprinted with permission from Inside Science, an editorially independent news product of the American Institute of Physics, a nonprofit organization dedicated to advancing, promoting and serving the physical sciences.