Oprah Winfrey (4-5 p.m., 6ABC) - A mother burned alive by her husband shares her message.

The Secret Life of the American Teenager (8-9 p.m., FAM) - The family drama 7th Heaven drew some flak for descending into teen-soap territory in its later seasons. But this new series from Heaven creator Brenda Hampton is unashamedly a teen soap; check the title. It's got less steam and more substance than the typical high-school drama, though. It's also got ex-teen queen Molly Ringwald as mom to young Amy (Shailene Woodley), whose unexpected pregnancy is the hook on which many of the story lines hang. Repeats at 9 p.m.

Late Show With David Letterman (11:35 p.m.-12:35 a.m., CBS3) - Actor Jack Black; Esperanza Spalding performs.

The Tonight Show With Jay Leno (11:50 p.m.-12:50 a.m., NBC10) - Actor Will Smith; tennis player Pete Sampras; Ed Harcourt performs.

Jimmy Kimmel Live (12:05-1:05 a.m., 6ABC) - Actor John Leguizamo; actress Meagan Good; Secondhand Serenade performs; special appearance by actor Bill Cosby.

The Late Late Show With Craig Ferguson (12:35-1:35 a.m., CBS3) - Comic Richard Lewis; Duffy performs.

Late Night With Conan O'Brien (12:50-1:50 a.m., NBC10) - Actress Sarah Jessica Parker; actor Aries Spears; They Might Be Giants perform.