The following chart shows how the top companies were ranked by their employees in our region:
| Size | Rank | Company | Employees |
| Large | 1 | Brown's Super Stores Inc. | 2,335 |
| Large | 2 | PricewaterhouseCoopers | 1,200 |
| Large | 3 | The University of Pennsylvania and Health System | 35,531 |
| Large | 4 | Chester County Intermediate Unit | 501 |
| Large | 5 | Campbell Soup Co. | 1,600 |
| Large | 6 | Special People In Northeast Inc. | 850 |
| Large | 7 | Airgas Inc. | 575 |
| Large | 8 | Philadelphia Insurance Companies | 685 |
| Large | 9 | Comcast Corp. | 10,349 |
| Large | 10 | SAP America Inc. | 1,511 |
| Large | 11 | Swarthmore College | 957 |
| Large | 12 | DaVita Inc. | 1,025 |
| Large | 13 | ReSearch Pharmaceutical Services Inc. | 597 |
| Large | 14 | The Vanguard Group Inc. | 9,000 |
| Large | 15 | Main Line Health | 9,046 |
| Large | 16 | Arcadia University | 932 |
| Large | 17 | SEI Investments Co. | 1,950 |
| Large | 18 | Toll Brothers Inc. | 656 |
| Large | 19 | FMC Corp. | 573 |
| Large | 20 | ACTS Retirement-Life Communities Inc. | 2,506 |
| Large | 21 | The Children's Hospital of Philadelphia | 10,000 |
| Large | 22 | Covance Inc. | 1,005 |
| Large | 23 | West Chester University | 2,048 |
| Large | 24 | Upper Darby School District | 1,454 |
| Large | 25 | Deborah Heart and Lung Center | 934 |
| Midsize | 1 | The Graham Company | 154 |
| Midsize | 2 | Power Windows & Siding | 150 |
| Midsize | 3 | Microsoft Corp. | 173 |
| Midsize | 4 | Artman Lutheran Home | 260 |
| Midsize | 5 | The Michaels Organization | 164 |
| Midsize | 6 | Analytical Graphics Inc. (AGI) | 205 |
| Midsize | 7 | Weston Solutions Inc. | 372 |
| Midsize | 8 | ASTM International | 157 |
| Midsize | 9 | The Hill at Whitemarsh | 250 |
| Midsize | 10 | TruMark Financial Credit Union | 271 |
| Midsize | 11 | Hill International Inc. | 260 |
| Midsize | 12 | CB Richard Ellis Inc. | 178 |
| Midsize | 13 | Urban Engineers Inc. | 306 |
| Midsize | 14 | Elliott-Lewis Corp. | 324 |
| Midsize | 15 | Worth & Co. Inc. | 407 |
| Midsize | 16 | Lincoln Investment Planning Inc. | 178 |
| Midsize | 17 | Maris Grove by Erickson Retirement Communities | 269 |
| Midsize | 18 | Vertex Inc. | 477 |
| Midsize | 19 | Genesis Rehab Services | 442 |
| Midsize | 20 | Corporate Synergies Group Inc. | 170 |
| Midsize | 21 | Penn Jersey Paper Co. | 300 |
| Midsize | 22 | Regional Women's Health Group L.L.C. | 369 |
| Midsize | 23 | Karr Barth Associates Inc. | 411 |
| Midsize | 24 | West Pharmaceutical Services Inc. | 362 |
| Midsize | 25 | Paul's Run Retirement Community | 340 |
| Midsize | 26 | Center For Family Services Inc. | 336 |
| Midsize | 27 | Edmund Optics Inc | 245 |
| Midsize | 28 | KlingStubbins Inc. | 281 |
| Midsize | 29 | Turner Construction Co. | 234 |
| Midsize | 30 | Chestnut Hill College | 471 |
| Midsize | 31 | Philadelphia Workforce Development Corp. | 161 |
| Midsize | 32 | Alpha Systems | 264 |
| Midsize | 33 | Mastery Charter Schools | 220 |
| Midsize | 34 | True Position Inc. | 278 |
| Midsize | 35 | National Label Co. Inc. | 300 |
| Small | 1 | Chariot Solutions | 50 |
| Small | 2 | Cherry Hill Volvo | 58 |
| Small | 3 | Charon Planning Corp. | 64 |
| Small | 4 | First Financial Group L.L.C. | 119 |
| Small | 5 | Balfour Beatty Communities, LLC | 77 |
| Small | 6 | Global Tax Management Inc. | 56 |
| Small | 7 | Evergreen Printing Co. | 85 |
| Small | 8 | Omni Hotel at Independence Park | 104 |
| Small | 9 | Miller's Insurance Agency | 53 |
| Small | 10 | Philadelphia Convention & Visitors Bureau | 64 |
| Small | 11 | Don Rosen Imports | 84 |
| Small | 12 | Excel Physical Therapy & Fitness | 126 |
| Small | 13 | Dunmore Corporation | 82 |
| Small | 14 | SofterWare Inc. | 104 |
| Small | 15 | NewAge Industries Inc. | 82 |
| Small | 16 | Fujirebio Diagnostics Inc. | 128 |
| Small | 17 | The Judge Group Inc. | 148 |
| Small | 18 | UGI Corp. | 57 |
| Small | 19 | Volpe and Koenig P.C. | 111 |
| Small | 20 | Movers Specialty Service Inc. | 142 |
| Small | 21 | Peirce College | 130 |
| Small | 22 | Merck Sharp & Dohme Federal Credit Union | 80 |
| Small | 23 | George Washington High School | 136 |
| Small | 24 | Community Legal Services Inc. | 114 |
| Small | 25 | Kimberton Whole Foods | 83 |
| Small | 26 | Penn Liberty Bank | 92 |
| Small | 27 | Dansko Inc | 146 |
| Small | 28 | Delaware County Regional Water | 118 |
| Small | 29 | Haas Group International Inc | 51 |
| Small | 30 | Creative Financial Group | 115 |
| Small | 31 | Triumph Group Inc. | 71 |
| Small | 32 | Kistler Tiffany Benefits | 83 |
| Small | 33 | Quaker Chemical Corp. | 104 |
| Small | 34 | Devine Brothers Inc. | 52 |
| Small | 35 | Community Action Agency Of Delaware County | 121 |
| Small | 36 | Maxwell Systems Inc | 67 |
| Small | 37 | The Radnor Hotel | 146 |
| Small | 38 | Compas Inc. | 54 |
| Small | 39 | Voice Systems Engineering Inc. | 95 |
| Small | 40 | Please Touch Museum | 145 |