Employees: 100,000

Market cap: $39.08 billion

1-year change: down 41.2 percent

Few companies are as omnipresent as Comcast in the Philadelphia region.

One Comcast Center towers over Center City. It owns the Flyers and Sixers.

Whether or not you have Comcast cable, high-speed Internet, or phone service doesn't prevent the letter carrier from delivering a weekly direct-mail pitch.

But look beyond the 10-county area and you will see how far Comcast has sprawled. As of March 31, Comcast had 24.1 million video customers, 15.3 million high-speed Internet customers, and 6.8 million phone customers.

DuPont Co.

Wilmington

Founded in 1802

CEO: Ellen J. Kullman

NYSE: DD

Employees: 60,000

Market cap: $25.73 billion

1-year change: down 39.4 percent

As difficult as the last year has been for the world's chemical companies, DuPont continues to direct its resources into the areas it believes are the future: agriculture, biosciences, safety and protection, and polymers. DuPont spends about 5 percent of sales, or $1.4 billion on research and development annually. While the Wilmington area remains the company's main research center, DuPont now has more than 20 R&D operations outside the United States.

Campbell Soup Co.

Camden

Founded in 1869

President/CEO: Douglas R. Conant