Goalie Ilya Bryzgalov, fighting off the flu, missed Friday's practice and likely will be sidelined for Saturday's key game against the visiting New York Rangers.
Sergei Bobrovsky is expected to get the start against the Rangers, who are 4-0 against the Flyers this season.
GM Paul Holmgren did not rule out Bryzgalov playing on Saturday.
"He's feeling better," Holmgren said, adding he will know more on Saturday morning.
Still, it's a long shot that Bryzgalov plays. He has not practiced in two days and figures to be weakened by the aftereffects of the flu.
The Rangers have outscored the Flyers, 14-6.
“Even though they’re a great team, I still believe we can beat them," Flyers winger Jaromir Jagr, a former Ranger, said after practice.
The last two meetings have been tight. The Flyers blew a 2-0 lead and dropped a 3-2 decision in the Winter Classic on Jan. 2. In the Rangers 5-2 win last Sunday, the game was tied at 2-2 early in the third period.
Here's a sobering stat for Flyers fans: Rangers goalie Henrik Lundqvist is 4-0 with a 1.50 GAA and .949 save percentage against the Orange and Black this season.
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Jason Bacashihua, recalled from the Phantoms on Thursday, replaced Bryzgalov at practice.
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The Flyers practiced shootout drills against Bobrovsky on Friday. They are 1-5 in shootouts this season and an NHL-worst 20-39 in franchise history.
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After sitting out Thursday's morning skate, winger James van Riemsdyk returned to practice. Afterward, he admitted to feeling in a fog as he recovers from a concussion.
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Follow Sam Carchidi on Twitter @BroadStBull.