Sunday, February 1, 2015

Zinc nasal gels can kill sense of smell

The doctors studied 25 patients who came to their clinic with "acute-onset anosmia," meaning they had suddenly lost their sense of smell. Using the so-called Bradford Hill criteria - nine tests to establish causality - they found that zinc gels used inside the nose led to a diminished or complete loss of smell.

Zinc nasal gels can kill sense of smell

Most people would do almost anything to get relief from a nose clogged by a cold. A small study by doctors at the University of California-San Diego, however, suggests avoiding nasal gels containing zinc — at least if you value your sense of smell.

The doctors studied 25 patients who came to their clinic with “acute-onset anosmia,” meaning they had suddenly lost their sense of smell. Using the so-called Bradford Hill criteria — nine tests to establish causality — they found that zinc gels used inside the nose led to a diminished or complete loss of smell.

While the over-the-counter gels are commonly used to prevent and treat colds, multiple scientific trials “have found that intranasal zinc is ineffective in preventing or reducing the duration of the common cold,” the researchers wrote in the Archives of Otolaryngology — Head & Neck Surgery.

Last month, the Food and Drug Administration warned consumers against three products — Zicam Cold Remedy Nasal Gel, Zicam Cold Remedy Nasal Swabs, and Zicam Cold Remedy Swabs, Kids Size — after the products were all associated with long-lasting or permanent losses of smell. The FDA said consumers should stop using the products after receiving 130 reports of consumers who lost their sense of smell.

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Check Up covers regional health news and a wide array of healthcare topics from pharmaceutical happenings to patient safety. Read about some of our bloggers here.

Portions of this blog may also be found in the Inquirer's Sunday Health Section.

Michael R. Cohen, R.Ph. President, Institute for Safe Medication Practices
Daniel R. Hoffman, Ph.D. President, Pharmaceutical Business Research Associates
Hooman Noorchashm, M.D., Ph.D. Cardiothoracic surgeon in the Philadelphia area
Amy J. Reed, M.D., Ph.D. Anesthesiologist and Surgical Intensivist in the Philadelphia Area
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