Saturday, December 27, 2014

Daniel Hoffman

Not so far from selling medicine in Conestoga Wagons

Wednesday, March 20, 2013, 6:00 AM
An email from a reader last week contained a link to an article (see here) about the FDA's proposal to ease the efficacy and safety standards for approving new Alzheimer's drugs. His terse comment was, "If it goes through, it will open great opportunities for snake oil salesmen." His brief remark... Read more

How big pharma discourages innovation

Monday, March 4, 2013, 9:50 AM
Big Pharma has been keeping itself afloat for some time on a number of myths. For several years, as investors saw the industry's business model breaking down, pharma tried to assuage them by perpetrating the myth that the emerging global markets (China, India, Russia) will restore earlier profit levels... Read more

How to make pharma companies into law abiding citizens

Tuesday, February 19, 2013, 9:00 AM
Last summer UC Berkeley professor Robert Reich reflected on the $3 billion penalty GlaxoSmithKline (GSK) paid for a whole range of violations. Their criminal behavior that led to the fine included: promoting an antidepressant approved only for adults to kids under 18; selling two other antidepressants... Read more

Clinical R&D deserves more due diligence

Monday, February 11, 2013, 12:01 PM
Late last month Citigroup published its 2013 overview for pharma, "Global Healthcare Road Ahead: 2013 Outlook." It constitutes a sobering counterview to the touts and boosters from those in the investment community who tried to prop up the recent earnings reports. The critical challenge for pharma... Read more

Pharma's clinical development at cross purposes with itself

Tuesday, January 22, 2013, 9:00 AM
Developing new products through clinical trials represents the lifeblood of branded pharmaceuticals. Unless companies can develop new products to replace the existing ones that lose patent protection, their revenues will erode as payers and patients fill prescriptions with less expensive generics... Read more

Social networks among trial sites set the pace of patient recruitment

Tuesday, January 8, 2013, 9:00 AM
Last October we reviewed some KMR data, combined it with our own findings (see here) and concluded that while the industry's overall productivity at developing new drugs has not substantially changed during the past decade, the period between starting a compound's clinical trials and its registration... Read more

Pharma facts 2012: Behind the curve on important health care changes

Saturday, January 5, 2013, 10:00 AM
Editor’s Note: All this week Check Up will be sharing one new Pharma fact a day that was an important breakthrough in the world of pharmaceuticals in 2012. Today, Check Up delves into health care changes. One of this year's memorable expressions came from a wise fellow at a major software company... Read more

Pharma facts 2012: Pharma wants the right to cry fire in a crowded theater

Friday, January 4, 2013, 10:00 AM
Editor’s Note: All this week Check Up will be sharing one new Pharma fact a day that was an important breakthrough in the world of pharmaceuticals in 2012. Today, Check Up delves into Pharma's right to promote drugs. This month the US 2nd Circuit Court of Appeals (New York, Connecticut, Vermont)... Read more

Pharma facts 2012: Health Care is the Real Fiscal Cliff

Thursday, January 3, 2013, 10:00 AM
Editor’s Note: All this week Check Up will be sharing one new Pharma fact a day that was an important breakthrough in the world of pharmaceuticals in 2012. Today, Check Up delves into the worries of the new health care. Health care costs already devour 18% of America's GDP. Between now and... Read more

Pharma facts 2012: The entire approach to cancer therapy may be ineffective

Wednesday, January 2, 2013, 10:00 AM
Editor’s Note: All this week Check Up will be sharing one new Pharma fact a day that was an important breakthrough in the world of pharmaceuticals in 2012. Today, Check Up delves into Pharma’s approach to cancer therapy. For a decade or more pharma's researchers have believed that the... Read more
About this blog

Check Up covers regional health news and a wide array of healthcare topics from pharmaceutical happenings to patient safety. Read about some of our bloggers here.

Portions of this blog may also be found in the Inquirer's Sunday Health Section.

Michael R. Cohen, R.Ph. President, Institute for Safe Medication Practices
Daniel R. Hoffman, Ph.D. President, Pharmaceutical Business Research Associates
Hooman Noorchashm, M.D., Ph.D. Cardiothoracic surgeon in the Philadelphia area
Amy J. Reed, M.D., Ph.D. Anesthesiologist and Surgical Intensivist in the Philadelphia Area
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