Oprah Winfrey (4 p.m., 6ABC) - Nicholas D. Kristof and Sheryl WuDunn; George Clooney, Ben Affleck, Demi Moore and Hillary Clinton.

NCIS (8 p.m., CBS3) - An NCIS agent is killed, and finding a woman in the desert holds the key to solving the crime.

A Presidential Address (8 p.m., 6ABC, NBC10, Fox29, other channels) - Announcement on troop commitments to Afghanistan.

90210 (8 p.m., CW57) - Adrianna makes a life-changing decision about her pill popping after a hospital visit with Navid.

NCIS: Los Angeles (9 p.m., CBS3) - An unmanned aerial vehicle loaded with a missile apparently falls into enemy hands, posing a threat to national security.

Melrose Place (9 p.m., CW57) - Amanda moves into the penthouse formerly occupied by Sydney and takes a very special interest in David.

Late Show With David Letterman (11:35 p.m., CBS3) - Julia Louis-Dreyfus; chef Guy Fieri; Carrie Underwood performs.

The Tonight Show With Conan O'Brien (11:35 p.m., NBC10) - Tobey Maguire; Rickie Lee Jones performs.

Jimmy Kimmel Live (12:05 a.m., 6ABC) - Author Magic Johnson; actor Kellan Lutz.

The Late Late Show With Craig Ferguson (12:35 a.m., CBS3) - Joel McHale; The Swell Season performs.

Late Night With Jimmy Fallon (12:35 a.m., NBC10) - Actress Kristen Stewart; actor Jamie Kennedy; the Avett Brothers perform.