Oprah Winfrey (4 p.m., 6ABC) - Ellen DeGeneres and wife Portia DeRossi.

Heroes (8 p.m., NBC10) - Claire is determined to get to the bottom of the Sorority Rush attacks.

House (8 p.m., Fox 29) - A teenage girl is brought to the hospital with severely swollen appendages after a wild night out.

NFL Football (8:30 p.m., ESPN) - The Broncos host the Pittsburgh Steelers in Denver.

Lie to Me (9:01 p.m., Fox 29) - Lightman, Foster and Reynolds head to Las Vegas to search for a missing World Series of Poker finalist.

The Big Bang Theory (9:31 p.m., CBS3) - Sheldon steps in when lovebirds Leonard and Penny have a fight.

CSI: Miami (10 p.m., CBS3) - In the first of a three-episode story arc, Dr. Ray Langston from the Las Vegas CSI unit comes to Miami to pursue a clue in a missing-girl case.

How the Beatles Rocked the Kremlin (10 p.m., WHYY TV12) - Russians who grew up listening to the Beatles describe how they found hope and inspiration in the Beatles' music and their message of rebellion - which may have played a role in the downfall of communism.

Late Show With David Letterman (11:35 p.m., CBS3) - Bill Murray; Gabourey "Gabby" Sidibe.

The Tonight Show With Conan O'Brien (11:35 p.m., NBC10) - Kelsey Grammer; Maj. Brian Dennis and his dog Nubs; David Gray performs.

Jimmy Kimmel Live (12:36 a.m., 6ABC) - Jamie Foxx; Toby Keith performs.

The Late Late Show With Craig Ferguson (12:37 a.m., CBS3) - Carla Gugino; author Dennis Lehane.