Oprah Winfrey (4 p.m., 6ABC) - Star Jones, Valerie Bertinelli and Marie Osmond talk about their public struggle to lose weight.

How I Met Your Mother (8 p.m., CBS3) - Barney and Ted offer to keep MacLaren's open during a big blizzard so they can meet up with some college girls.

Great American Road Trip (8 p.m., NBC10) - The families leave Missouri and travel into Kansas, Oklahoma and Texas. Fathers compete in a barbecue challenge.

Rules of Engagement (8:30 p.m., CBS3) - Jeff's chauvinist father, who expects Audrey to wait on him hand and foot even under the best of circumstances, extends his visit after spraining his ankle.

Two and a Half Men (9 p.m., CBS3) - Convinced that Alan is not appreciated by his family, Melissa asks him to live with her and her mother.

The Big Bang Theory (9:31 p.m., CBS3) - Sheldon introduces Penny to the wonderful world of Internet games.

Late Show With David Letterman (11:35 p.m., CBS3) - Katherine Heigl; comic Jeff Altman; Spinnerette performs.

The Tonight Show With Conan O'Brien (11:35 p.m., NBC10) - Adam Sandler; Peter Sarsgaard; Kate Voegele performs.

Jimmy Kimmel Live (12:05 a.m., 6ABC) - Actor David Arquette; actress Jill Wagner; Linkin Park performs.

The Late Late Show With Craig Ferguson (12:35 a.m., CBS3) - Comic Margaret Cho; author Michael Lewis; Eric Church performs.

Late Night With Jimmy Fallon (12:35 a.m., NBC10) - Actor Will Arnett; actress Emmanuelle Chriqui; Tom Jones performs.